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-Structure paper
Title | Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation. |
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Journal, issue, pages | J. Mol. Biol., Vol. 428, Page 2981-2988, Year 2016 |
Publish date | Jun 13, 2016 (structure data deposition date) |
Authors | Prota, A.E. / Setter, J. / Waight, A.B. / Bargsten, K. / Murga, J. / Diaz, J.F. / Steinmetz, M.O. |
External links | J. Mol. Biol. / PubMed:27395016 |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | PDB-5la6: |
Chemicals | ChemComp-GTP: ChemComp-MG: ChemComp-CA: ChemComp-GDP: ChemComp-X3H: ChemComp-ACP: ChemComp-HOH: |
Source |
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Keywords | CELL CYCLE / TUBULIN FOLD / CYTOSKELETON / MICROTUBULE |