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Structure paper

TitleElucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations.
Journal, issue, pagesBiochemistry, Vol. 55, Page 3692-3701, Year 2016
Publish dateDec 18, 2015 (structure data deposition date)
AuthorsGoh, B.C. / Wu, H. / Rynkiewicz, M.J. / Schulten, K. / Seaton, B.A. / McCormack, F.X.
External linksBiochemistry / PubMed:27324153
MethodsX-ray diffraction
Resolution1.8 - 2.2 Å
Structure data

PDB-5ffr:
Crystal Structure of Surfactant Protein-A complexed with phosphocholine
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-5ffs:
Crystal Structure of Surfactant Protein-A Y164A Mutant
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-5fft:
Crystal Structure of Surfactant Protein-A Y221A Mutant
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-PC:
PHOSPHOCHOLINE

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsSUGAR BINDING PROTEIN / COLLECTIN / CARBOHYDRATE BINDING / LECTIN / LIPID BINDING

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