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Structure paper

TitleInhibiting complex IL-17A and IL-17RA interactions with a linear peptide.
Journal, issue, pagesSci Rep, Vol. 6, Page 26071-26071, Year 2016
Publish dateJan 11, 2016 (structure data deposition date)
AuthorsLiu, S. / Desharnais, J. / Sahasrabudhe, P.V. / Jin, P. / Li, W. / Oates, B.D. / Shanker, S. / Banker, M.E. / Chrunyk, B.A. / Song, X. ...Liu, S. / Desharnais, J. / Sahasrabudhe, P.V. / Jin, P. / Li, W. / Oates, B.D. / Shanker, S. / Banker, M.E. / Chrunyk, B.A. / Song, X. / Feng, X. / Griffor, M. / Jimenez, J. / Chen, G. / Tumelty, D. / Bhat, A. / Bradshaw, C.W. / Woodnutt, G. / Lappe, R.W. / Thorarensen, A. / Qiu, X. / Withka, J.M. / Wood, L.D.
External linksSci Rep / PubMed:27184415
MethodsX-ray diffraction
Resolution2.2 - 3 Å
Structure data

PDB-5hhv:
Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-5hhx:
Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM/INHIBITOR / IL-17 / inflammation / inhibitor / complex crystal structure / IMMUNE SYSTEM-INHIBITOR complex

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