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Structure paper

TitleStructural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
Journal, issue, pagesBiochemistry, Vol. 55, Page 2979-2991, Year 2016
Publish dateFeb 17, 2016 (structure data deposition date)
AuthorsWalton, W.G. / Ahmad, S. / Little, M.S. / Kim, C.S. / Tyrrell, J. / Lin, Q. / Di, Y.P. / Tarran, R. / Redinbo, M.R.
External linksBiochemistry / PubMed:27145151
MethodsX-ray diffraction
Resolution2.544 - 2.598 Å
Structure data

PDB-5i7j:
Crystal Structure of Human SPLUNC1 Disulfide Mutant M3 (I76C, V214C)
Method: X-RAY DIFFRACTION / Resolution: 2.544 Å

PDB-5i7k:
Crystal Structure of Human SPLUNC1 Dolphin Mutant D1 (G58A, S61A, G62E, G63D, G66D, I67T)
Method: X-RAY DIFFRACTION / Resolution: 2.552 Å

PDB-5i7l:
Crystal Structure of SPLUNC1 Disulfide Mutant M2 (A48C, V253C)
Method: X-RAY DIFFRACTION / Resolution: 2.598 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsANTIMICROBIAL PROTEIN / Innate pulmonary defense protein / Surfactant / Antimicrobial / Airway

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