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-Structure paper
Title | Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex. |
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Journal, issue, pages | J. Med. Chem., Vol. 59, Page 5095-5101, Year 2016 |
Publish date | Dec 21, 2015 (structure data deposition date) |
![]() | Sutherell, C.L. / Tallant, C. / Monteiro, O.P. / Yapp, C. / Fuchs, J.E. / Fedorov, O. / Siejka, P. / Muller, S. / Knapp, S. / Brenton, J.D. ...Sutherell, C.L. / Tallant, C. / Monteiro, O.P. / Yapp, C. / Fuchs, J.E. / Fedorov, O. / Siejka, P. / Muller, S. / Knapp, S. / Brenton, J.D. / Brennan, P.E. / Ley, S.V. |
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Methods | X-ray diffraction |
Resolution | 1.47 - 2.3 Å |
Structure data | ![]() PDB-5fh6: ![]() PDB-5fh7: ![]() PDB-5fh8: |
Chemicals | ![]() ChemComp-5XM: ![]() ChemComp-HOH: ![]() ChemComp-EDO: ![]() ChemComp-5XL: ![]() ChemComp-5XK: ![]() ChemComp-DMS: |
Source |
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![]() | TRANSCRIPTION / PBRM1 / BRG1-associated factor 180 / chromatin remodeling |