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Structure paper

TitleStructural insights into inhibition of lipid I production in bacterial cell wall synthesis.
Journal, issue, pagesNature, Vol. 533, Page 557-560, Year 2016
Publish dateJul 15, 2015 (structure data deposition date)
AuthorsChung, B.C. / Mashalidis, E.H. / Tanino, T. / Kim, M. / Matsuda, A. / Hong, J. / Ichikawa, S. / Lee, S.Y.
External linksNature / PubMed:27088606
MethodsX-ray diffraction
Resolution2.95 Å
Structure data

PDB-5ckr:
Crystal Structure of MraY in complex with Muraymycin D2
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-57M:
Muraymycin D2

ChemComp-HOH:
WATER

Source
  • aquifex aeolicus (strain vf5) (bacteria)
KeywordsTRANSFERASE/ANTIBIOTIC / ALPHA-HELICAL / PNPT Superfamily / phospho-MurNAc-pentapeptide translocase / Membrane Protein / Bacterial cell wall / synthesis / natural product inhibitor / TRANSFERASE-ANTIBIOTIC complex

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