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TitleRhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA Damage.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 11083-11093, Year 2016
Publish dateSep 27, 2014 (structure data deposition date)
AuthorsLi, Q. / Huang, Y. / Liu, X. / Gan, J. / Chen, H. / Yang, C.G.
External linksJ. Biol. Chem. / PubMed:27015802
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-4rfr:
Complex structure of AlkB/rhein
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-RHN:
4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE/INHIBITOR / protein-inhibitor complex / demethylation / AlkB family / Jellyroll Fold / demethylase / nucleic acid binding / nucleus / OXIDOREDUCTASE-INHIBITOR complex

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