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Structure paper

TitleInduced Structural Disorder as a Molecular Mechanism for Enzyme Dysfunction in Phosphoglucomutase 1 Deficiency.
Journal, issue, pagesJ. Mol. Biol., Vol. 428, Page 1493-1505, Year 2016
Publish dateNov 11, 2015 (structure data deposition date)
AuthorsStiers, K.M. / Kain, B.N. / Graham, A.C. / Beamer, L.J.
External linksJ. Mol. Biol. / PubMed:26972339
MethodsX-ray diffraction
Resolution1.85 - 2.65 Å
Structure data

PDB-5epc:
Crystal structure of wild-type human phosphoglucomutase 1
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-5f9c:
Crystal structure of the G121R mutant of human phosphoglucomutase 1
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-5hsh:
Crystal structure of the G291R mutant of human phosphoglucomutase 1
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / isomerase metabolism / phosphoglucomutase / enzyme / missense mutant

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