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Structure paper

TitleMolecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateFeb 26, 2016 (structure data deposition date)
AuthorsBhattacharyya, M. / Stratton, M.M. / Going, C.C. / McSpadden, E.D. / Huang, Y. / Susa, A.C. / Elleman, A. / Cao, Y.M. / Pappireddi, N. / Burkhardt, P. ...Bhattacharyya, M. / Stratton, M.M. / Going, C.C. / McSpadden, E.D. / Huang, Y. / Susa, A.C. / Elleman, A. / Cao, Y.M. / Pappireddi, N. / Burkhardt, P. / Gee, C.L. / Barros, T. / Schulman, H. / Williams, E.R. / Kuriyan, J.
External linksElife / PubMed:26949248
MethodsX-ray diffraction
Resolution1.75 - 3 Å
Structure data

PDB-5ig0:
Crystal structure of S. rosetta CaMKII hub
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-5ig1:
Crystal structure of S. rosetta CaMKII kinase domain
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-5ig3:
Crystal structure of the human CaMKII-alpha hub
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-5ig4:
Crystal structure of N. vectensis CaMKII-A hub
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-5ig5:
Crystal structure of N. vectensis CaMKII-B hub at pH 4.2
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

Source
  • salpingoeca rosetta (strain atcc 50818 / bsb-021) (eukaryote)
  • salpingoeca rosetta (eukaryote)
  • homo sapiens (human)
  • nematostella vectensis (starlet sea anemone)
KeywordsTRANSFERASE / Ca2+/CaM-dependent kinase / choanoflagellate / open-spiral / Ca2+/CaM-dependent kinase alpha / hub / sea anemone / closed-ring / peptide docking

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