+Search query
-Structure paper
Title | Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides. |
---|---|
Journal, issue, pages | J. Org. Chem., Vol. 81, Page 2261-2279, Year 2016 |
Publish date | Aug 17, 2015 (structure data deposition date) |
![]() | Kel In, A.V. / Zlatev, I. / Harp, J. / Jayaraman, M. / Bisbe, A. / O Shea, J. / Taneja, N. / Manoharan, R.M. / Khan, S. / Charisse, K. ...Kel In, A.V. / Zlatev, I. / Harp, J. / Jayaraman, M. / Bisbe, A. / O Shea, J. / Taneja, N. / Manoharan, R.M. / Khan, S. / Charisse, K. / Maier, M.A. / Egli, M. / Rajeev, K.G. / Manoharan, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.2 - 1.993 Å |
Structure data | ![]() PDB-5d8t: ![]() PDB-5dek: ![]() PDB-5der: |
Chemicals | ![]() ChemComp-NCO: ![]() ChemComp-HOH: |
Source |
|
![]() | RNA / modified base / oligonucleotide |