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-Structure paper
Title | Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies. |
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Journal, issue, pages | Mbio, Vol. 7, Page e02154-e02115, Year 2016 |
Publish date | Jan 12, 2016 (structure data deposition date) |
![]() | Bornholdt, Z.A. / Ndungo, E. / Fusco, M.L. / Bale, S. / Flyak, A.I. / Crowe, J.E. / Chandran, K. / Saphire, E.O. |
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Methods | X-ray diffraction |
Resolution | 3.3 Å |
Structure data | ![]() PDB-5hj3: |
Source |
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![]() | VIRAL PROTEIN/IMMUNE SYSTEM / Ebola virus / EOV / Ebolavirus / GP / glycoprotein / GPcl / cleaved / primed / proteolytically / receptor binding pocket / crest / trough / MR72 / KZ52 / broadly neutralizing / VIRAL PROTEIN-IMMUNE SYSTEM complex |