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-Structure paper
Title | Structural Analysis of the Tobramycin and Gentamicin Clinical Resistome Reveals Limitations for Next-generation Aminoglycoside Design. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 11, Page 1339-1346, Year 2016 |
Publish date | Jul 8, 2015 (structure data deposition date) |
![]() | Bassenden, A.V. / Rodionov, D. / Shi, K. / Berghuis, A.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.5 - 1.7 Å |
Structure data | ![]() PDB-5cfs: ![]() PDB-5cft: |
Chemicals | ![]() ChemComp-MN: ![]() ChemComp-TOY: ![]() ChemComp-APC: ![]() ChemComp-PG0: ![]() ChemComp-P6G: ![]() ChemComp-HOH: ![]() ChemComp-51G: |
Source |
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![]() | transferase/antibiotic / antibiotic resistance / nucleotidyltransferase / AMPCPP / tobramycin / Rossmann fold / transferase-antibiotic complex / gentamicin |