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Structure paper

TitleStructural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.
Journal, issue, pagesEmbo J., Vol. 35, Page 759-772, Year 2016
Publish dateAug 19, 2015 (structure data deposition date)
AuthorsSeifert, F.U. / Lammens, K. / Stoehr, G. / Kessler, B. / Hopfner, K.P.
External linksEmbo J. / PubMed:26896444
MethodsX-ray diffraction
Resolution2.503 - 3 Å
Structure data

PDB-5da9:
ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with the Rad50-binding domain of Mre11
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5dac:
ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 2.503 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

ChemComp-AES:
4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE / protease inhibitor*YM

Source
  • chaetomium thermophilum var. thermophilum dsm 1495 (fungus)
  • synthetic construct (others)
KeywordsHYDROLASE / ATPase / ATPyS bound

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