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-Structure paper
Title | The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. |
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Journal, issue, pages | J. Biol. Chem., Vol. 291, Page 7256-7266, Year 2016 |
Publish date | Apr 21, 2010 (structure data deposition date) |
![]() | Ho, N.A. / Dawes, S.S. / Crowe, A.M. / Casabon, I. / Gao, C. / Kendall, S.L. / Baker, E.N. / Eltis, L.D. / Lott, J.S. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 2.6 Å |
Structure data | ![]() PDB-3mnl: ![]() PDB-5cw8: ![]() PDB-5cxg: ![]() PDB-5cxi: |
Chemicals | ![]() ChemComp-PGE: ![]() ChemComp-HOH: ![]() ChemComp-55X: ![]() ChemComp-PEG: ![]() ChemComp-5TW: |
Source |
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![]() | TRANSCRIPTION REGULATOR / tetR family of transcriptional regulator / all-helical / DNA-binding / hydrophobic ligand-binding / Structural Genomics / TB Structural Genomics Consortium / TBSGC / Transcriptional repressor / TetR family Transcriptional repressor / cholesterol catabolism / CoA thioester ligand / TRANSCRIPTION / TetR family Tcholesterol catabolism |