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TitleHuman cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateOct 8, 2015 (structure data deposition date)
AuthorsFang, Q. / Chen, P. / Wang, M. / Fang, J. / Yang, N. / Li, G. / Xu, R.M.
External linksElife / PubMed:26812545
MethodsX-ray diffraction
Resolution2.809 Å
Structure data

PDB-5e5a:
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
Method: X-RAY DIFFRACTION / Resolution: 2.809 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • xenopus laevis (African clawed frog)
  • human herpesvirus 5 strain towne
KeywordsPROTEIN BINDING/VIRAL PROTEIN/DNA / NCP / IE1 / hCMV / CTD / PROTEIN BINDING-VIRAL PROTEIN-DNA complex

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