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Structure paper

TitleA new crystal form of human transthyretin obtained with a curcumin derived ligand.
Journal, issue, pagesJ. Struct. Biol., Vol. 194, Page 8-17, Year 2016
Publish dateNov 26, 2015 (structure data deposition date)
AuthorsPolsinelli, I. / Nencetti, S. / Shepard, W. / Ciccone, L. / Orlandini, E. / Stura, E.A.
External linksJ. Struct. Biol. / PubMed:26796656
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-5ezp:
Human transthyretin (TTR) complexed with 4-hydroxy-chalcone
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-IPJ:
4-hydroxy-chalcone

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Human transthyretin (TTR) / chalcone / inhibitor complex / new crystal polymorph

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