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TitleStructural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.
Journal, issue, pagesPlos Pathog., Vol. 12, Page e1005362-e1005362, Year 2016
Publish dateJul 30, 2015 (structure data deposition date)
AuthorsMeinke, G. / Phelan, P.J. / Shin, J. / Gagnon, D. / Archambault, J. / Bohm, A. / Bullock, P.A.
External linksPlos Pathog. / PubMed:26735515
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-5cyn:
JC Virus large T-antigen origin binding domain F258L mutant
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • jc polyomavirus
Keywordsviral protein / dna binding protein / DNA binding domain / origin binding domain

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