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TitleStructural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR
Journal, issue, pagesFEBS J., Vol. 283, Page 541-555, Year 2016
Publish dateMar 7, 2014 (structure data deposition date)
AuthorsHorvath, G. / Bencsura, A. / Simon, A. / Tochtrop, G.P. / DeKoster, G.T. / Covey, D.F. / Cistola, D.P. / Toke, O.
External linksFEBS J. / PubMed:26613247
MethodsNMR (solution)
Structure data

PDB-2mm3:
Solution NMR structure of the ternary complex of human ileal bile acid-binding protein with glycocholate and glycochenodeoxycholate
Method: SOLUTION NMR

Chemicals

ChemComp-GCH:
GLYCOCHOLIC ACID

ChemComp-CHO:
GLYCOCHENODEOXYCHOLIC ACID / detergent*YM

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / lipid-binding protein / orthogonal beta sheets / positive binding cooperativity / site-selectivity / enterohepatic circulation

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