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Structure paper

TitleStructural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I.
Journal, issue, pagesNucleic Acids Res., Vol. 43, Page 11031-11046, Year 2015
Publish dateNov 20, 2014 (structure data deposition date)
AuthorsTan, K. / Zhou, Q. / Cheng, B. / Zhang, Z. / Joachimiak, A. / Tse-Dinh, Y.C.
External linksNucleic Acids Res. / PubMed:26490962
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-4rul:
Crystal structure of full-length E.Coli topoisomerase I in complex with ssDNA
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • escherichia coli dh1 (bacteria)
  • synthetic construct (others)
KeywordsISOMERASE/DNA / TOPOISOMERASE 1A / ISOMERASE-DNA complex

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