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TitleInhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 13225-13230, Year 2015
Publish dateJul 25, 2015 (structure data deposition date)
AuthorsLee, S. / Greenlee, E.B. / Amick, J.R. / Ligon, G.F. / Lillquist, J.S. / Natoli, E.J. / Hadari, Y. / Alvarado, D. / Schlessinger, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:26460020
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-5cus:
Crystal Structure of sErbB3-Fab3379 Complex
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / ErbB3 / Antibody

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