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Structure paper

TitleN-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 13318-13323, Year 2015
Publish dateSep 8, 2015 (structure data deposition date)
AuthorsJin, N. / Wang, Y. / Crawford, F. / White, J. / Marrack, P. / Dai, S. / Kappler, J.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:26453556
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-5dmk:
Crystal Structure of IAg7 in complex with RLGL-WE14
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Chromogranin A / Type I Diabetes / T cell / fusion protein

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