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Structure paper

TitleStructural basis for gene regulation by a B12-dependent photoreceptor.
Journal, issue, pagesNature, Vol. 526, Page 536-541, Year 2015
Publish dateJun 25, 2015 (structure data deposition date)
AuthorsJost, M. / Fernandez-Zapata, J. / Polanco, M.C. / Ortiz-Guerrero, J.M. / Chen, P.Y. / Kang, G. / Padmanabhan, S. / Elias-Arnanz, M. / Drennan, C.L.
External linksNature / PubMed:26416754
MethodsX-ray diffraction
Resolution2.15 - 3.89 Å
Structure data

PDB-5c8a:
Crystal structure of a truncated form of Thermus thermophilus CarH bound to adenosylcobalamin (dark state)
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-5c8d:
Crystal structure of full-length Thermus thermophilus CarH bound to adenosylcobalamin (dark state)
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5c8e:
Crystal structure of Thermus thermophilus CarH bound to adenosylcobalamin and a 26-bp DNA segment
Method: X-RAY DIFFRACTION / Resolution: 3.89 Å

PDB-5c8f:
Crystal structure of light-exposed full-length Thermus thermophilus CarH bound to cobalamin
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-B12:
COBALAMIN

ChemComp-5AD:
5'-DEOXYADENOSINE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • thermus thermophilus (bacteria)
  • thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039) (bacteria)
  • thermus thermophilus hb27 (bacteria)
KeywordsTRANSCRIPTIONAL REGULATOR / Transcription factor / light sensor / adenosylcobalamin-binding / DNA-binding / TRANSCRIPTION / Transcription regulator/DNA / Transcription regulator-DNA complex

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