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Structure paper

TitleCrystallographic Studies of Two Variants of Pseudomonas Aeruginosa Impdh with Impaired Allosteric Regulation
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 71, Page 1890-, Year 2015
Publish dateFeb 6, 2015 (structure data deposition date)
AuthorsLabesse, G. / Alexandre, T. / Gelin, M. / Haouz, A. / Munier-Lehmann, H.
External linksActa Crystallogr. ,Sect. D / PubMed:26327379
MethodsX-ray diffraction
Resolution1.652 - 1.951 Å
Structure data

PDB-5ahl:
Apo-form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 1.951 Å

PDB-5ahm:
IMP-bound form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

PDB-5ahn:
IMP-bound form of the D199N mutant of IMPDH from Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 1.652 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-IMP:
INOSINIC ACID

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MG:
Unknown entry

Source
  • pseudomonas aeruginosa pao1 (bacteria)
KeywordsOXIDOREDUCTASE / CBS MODULE / DELETION MUTANT / ALLOSTERIC REGU NUCLEOTIDE METABOLISM / POINT MUTANT / ALLOSTERIC REGULATION NUCLEOTIDE METABOLISM

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