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-Structure paper
Title | Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 7549-7556, Year 2015 |
Publish date | Jul 9, 2015 (structure data deposition date) |
Authors | Yokoyama, T. / Mizuguchi, M. / Ostermann, A. / Kusaka, K. / Niimura, N. / Schrader, T.E. / Tanaka, I. |
External links | J. Med. Chem. / PubMed:26314394 |
Methods | X-ray diffraction / neutron diffraction |
Resolution | 1.402 - 1.7 Å |
Structure data | PDB-5cg5: PDB-5cg6: |
Chemicals | ChemComp-MG: ChemComp-RIS: ChemComp-DOD: ChemComp-IPE: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBOTOR / prenyl transferase / bisphophonate / osteoprosis / inhibitor / TRANSFERASE-TRANSFERASE INHIBOTOR complex / TRANSFERASE/TRANSFERASE INHIBITOR / bisphosphonate / TRANSFERASE-TRANSFERASE INHIBITOR complex |