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Structure paper

TitleMextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Journal, issue, pagesGenes Dev., Vol. 29, Page 1835-, Year 2015
Publish dateAug 9, 2015 (structure data deposition date)
AuthorsPeter, D. / Weber, R. / Koene, C. / Chung, M.-Y. / Ebertsch, L. / Truffault, V. / Weichenrieder, O. / Igreja, C. / Izaurralde, E.
External linksGenes Dev. / PubMed:26294658
MethodsX-ray diffraction
Resolution1.66 - 2.16 Å
Structure data

PDB-5abu:
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog
Method: X-RAY DIFFRACTION / Resolution: 2.16 Å

PDB-5abv:
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

PDB-5abx:
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli and cap analog
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

PDB-5aby:
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-GTG:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MGP:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

Source
  • drosophila melanogaster (fruit fly)
  • caenorhabditis elegans (invertebrata)
KeywordsTRANSLATION / GENE REGULATION / CAP BINDING PROTEIN / 4E BINDING PROTEIN

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