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TitleStructural mechanism for signal transduction in RXR nuclear receptor heterodimers.
Journal, issue, pagesNat Commun, Vol. 6, Page 8013-8013, Year 2015
Publish dateMay 5, 2015 (structure data deposition date)
AuthorsKojetin, D.J. / Matta-Camacho, E. / Hughes, T.S. / Srinivasan, S. / Nwachukwu, J.C. / Cavett, V. / Nowak, J. / Chalmers, M.J. / Marciano, D.P. / Kamenecka, T.M. ...Kojetin, D.J. / Matta-Camacho, E. / Hughes, T.S. / Srinivasan, S. / Nwachukwu, J.C. / Cavett, V. / Nowak, J. / Chalmers, M.J. / Marciano, D.P. / Kamenecka, T.M. / Shulman, A.I. / Rance, M. / Griffin, P.R. / Bruning, J.B. / Nettles, K.W.
External linksNat Commun / PubMed:26289479
MethodsX-ray diffraction
Resolution3.221 Å
Structure data

PDB-4zo1:
Crystal Structure of the T3-bound TR-beta Ligand-binding Domain in complex with RXR-alpha
Method: X-RAY DIFFRACTION / Resolution: 3.221 Å

Chemicals

ChemComp-T3:
3,5,3'TRIIODOTHYRONINE

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Nuclear receptor / transcription factor / ligand binding / protein-ligand complex

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