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Structure paper

TitleStructural basis for the blockade of MATE multidrug efflux pumps.
Journal, issue, pagesNat Commun, Vol. 6, Page 7995-7995, Year 2015
Publish dateJun 23, 2015 (structure data deposition date)
AuthorsRadchenko, M. / Symersky, J. / Nie, R. / Lu, M.
External linksNat Commun / PubMed:26246409
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-5c6n:
protein A
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5c6o:
protein B
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5c6p:
protein C
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-4YH:
(2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile

Source
  • bacillus halodurans (strain atcc baa-125 / dsm 18197 / ferm 7344 / jcm 9153 / c-125) (bacteria)
  • neisseria gonorrhoeae (strain atcc 700825 / fa 1090) (bacteria)
  • escherichia coli (E. coli)
KeywordsTRANSPORT PROTEIN / protein A / protein binding / protein

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