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Structure paper

TitleSubstrate-bound structure of the E. coli multidrug resistance transporter MdfA
Journal, issue, pagesCell Res., Vol. 25, Page 1060-1073, Year 2015
Publish dateMay 7, 2015 (structure data deposition date)
AuthorsHeng, J. / Zhao, Y. / Liu, M. / Liu, Y. / Fan, J. / Wang, X. / Zhang, X.C.
External linksCell Res. / PubMed:26238402
MethodsX-ray diffraction
Resolution2 - 2.45 Å
Structure data

PDB-4zow:
Crystal structure of E. coli multidrug transporter MdfA in complex with chloramphenicol
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-4zp0:
Crystal structure of E. coli multidrug transporter MdfA in complex with deoxycholate
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4zp2:
Crystal structure of E. coli multidrug transporter MdfA in complex with n-dodecyl-N,N-dimethylamine-N-oxide
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CLM:
CHLORAMPHENICOL / antibiotic*YM

ChemComp-HOH:
WATER

ChemComp-DXC:
(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID / detergent*YM

ChemComp-LDA:
LAURYL DIMETHYLAMINE-N-OXIDE / LDAO, detergent*YM

Source
  • escherichia coli (strain k12) (bacteria)
KeywordsTRANSPORT PROTEIN / MFS family / Multi-drug antiporter / MDFA / Cm

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