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Structure paper

TitleStructural basis of the Norrin-Frizzled 4 interaction.
Journal, issue, pagesCell Res., Vol. 25, Page 1078-1081, Year 2015
Publish dateJul 16, 2015 (structure data deposition date)
AuthorsShen, G. / Ke, J. / Wang, Z. / Cheng, Z. / Gu, X. / Wei, Y. / Melcher, K. / Xu, H.E. / Xu, W.
External linksCell Res. / PubMed:26227961
MethodsX-ray diffraction
Resolution2.4 - 3.8 Å
Structure data

PDB-5cl1:
Complex structure of Norrin with human Frizzled 4
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

PDB-5cm4:
Crystal structure of human Frizzled 4 Cysteine-Rich Domain (CRD)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • escherichia coli o157:h7 (bacteria)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Wnt / Norrin / Frizzled / Wnt signaling / Norrin signaling / Frizzled 4 extracelluar domain / Cysteine-Rich Domain

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