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Structure paper

TitleRNA degradation paths in a 12-subunit nuclear exosome complex.
Journal, issue, pagesNature, Vol. 524, Page 54-58, Year 2015
Publish dateJun 12, 2015 (structure data deposition date)
AuthorsMakino, D.L. / Schuch, B. / Stegmann, E. / Baumgartner, M. / Basquin, C. / Conti, E.
External linksNature / PubMed:26222026
MethodsX-ray diffraction
Resolution2.1 - 4.6 Å
Structure data

PDB-5c0w:
Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates
Method: X-RAY DIFFRACTION / Resolution: 4.6 Å

PDB-5c0x:
Structure of a 12-subunit nuclear exosome complex bound to structured RNA
Method: X-RAY DIFFRACTION / Resolution: 3.812 Å

PDB-5c0y:
Crystal structure of the Rrp6 catalytic domain bound to poly(U) RNA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • synthetic construct (others)
  • saccharomyces cerevisiae s288c (yeast)
KeywordsHYDROLASE/RNA / hydrolase / RNA / nuclease / hydrolase-RNA complex / protein-RNA complex / Exoribonuclease / RNA processing and degradation / nuclear RNA Exosome

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