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TitleThe La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence.
Journal, issue, pagesNucleic Acids Res., Vol. 43, Page 8077-8088, Year 2015
Publish dateApr 15, 2015 (structure data deposition date)
AuthorsLahr, R.M. / Mack, S.M. / Heroux, A. / Blagden, S.P. / Bousquet-Antonelli, C. / Deragon, J.M. / Berman, A.J.
External linksNucleic Acids Res. / PubMed:26206669
MethodsX-ray diffraction
Resolution1.86 - 2.2 Å
Structure data

PDB-4zc4:
Crystal structure of LARP1-unique domain DM15
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

PDB-5c0v:
Structure of the LARP1-unique domain DM15
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / RNA-binding / Heat-like / mRNA / helical repeat

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