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TitleVaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 9346-9351, Year 2015
Publish dateJan 15, 2015 (structure data deposition date)
AuthorsWinarski, K.L. / Thornburg, N.J. / Yu, Y. / Sapparapu, G. / Crowe, J.E. / Spiller, B.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:26170302
MethodsX-ray diffraction
Resolution2.001 - 2.74 Å
Structure data

PDB-4xnm:
Antibody Influenza H5 Complex
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

PDB-4xnq:
Antibody hemagglutinin Complexes
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

PDB-4xrc:
Antibody hemagglutinin Complexes
Method: X-RAY DIFFRACTION / Resolution: 2.74 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • influenza a virus
KeywordsViral protein/Immune system / Antibody / Influenza / Neutralization / Viral protein-Immune system complex / hemagglutinin

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