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Structure paper

TitleMolecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Journal, issue, pagesStructure, Vol. 23, Page 1459-1469, Year 2015
Publish dateNov 18, 2014 (structure data deposition date)
AuthorsQuaile, A.T. / Urbanus, M.L. / Stogios, P.J. / Nocek, B. / Skarina, T. / Ensminger, A.W. / Savchenko, A.
External linksStructure / PubMed:26146184
MethodsX-ray diffraction
Resolution1.954 - 3.408 Å
Structure data

PDB-4wz0:
Crystal structure of U-box 1 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris
Method: X-RAY DIFFRACTION / Resolution: 1.954 Å

PDB-4wz2:
Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, Ile175Met mutant
Method: X-RAY DIFFRACTION / Resolution: 3.408 Å

PDB-4wz3:
Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4xi1:
Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, wild-type
Method: X-RAY DIFFRACTION / Resolution: 2.983 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-HEZ:
HEXANE-1,6-DIOL

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

Source
  • legionella pneumophila (strain paris) (bacteria)
  • legionella pneumophila (bacteria)
  • homo sapiens (human)
KeywordsLIGASE / alpha/beta protein / effector / structural genomics / PSI-Biology / MCSG / Midwest Center for Structural Genomics / activating enzyme

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