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TitleStructural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 17935-17945, Year 2015
Publish dateApr 9, 2015 (structure data deposition date)
AuthorsWu, Y. / Koharudin, L.M. / Mehrens, J. / DeLucia, M. / Byeon, C.H. / Byeon, I.J. / Calero, G. / Ahn, J. / Gronenborn, A.M.
External linksJ. Biol. Chem. / PubMed:26045556
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-4z8l:
Crystal structure of DCAF1/SIV-MND VPX/MND SAMHD1 NTD ternary complex
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • simian immunodeficiency virus
  • mandrillus sphinx (mandrill)
KeywordsViral Protein/VPX-BINDING PROTEIN / HIV / antiviral defense / Viral Protein-VPX-BINDING PROTEIN complex

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