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TitleNon-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
Journal, issue, pagesStructure, Vol. 23, Page 1293-1304, Year 2015
Publish dateApr 15, 2015 (structure data deposition date)
AuthorsJarvis, T.C. / Davies, D.R. / Hisaminato, A. / Resnicow, D.I. / Gupta, S. / Waugh, S.M. / Nagabukuro, A. / Wadatsu, T. / Hishigaki, H. / Gawande, B. ...Jarvis, T.C. / Davies, D.R. / Hisaminato, A. / Resnicow, D.I. / Gupta, S. / Waugh, S.M. / Nagabukuro, A. / Wadatsu, T. / Hishigaki, H. / Gawande, B. / Zhang, C. / Wolk, S.K. / Mayfield, W.S. / Nakaishi, Y. / Burgin, A.B. / Stewart, L.J. / Edwards, T.E. / Gelinas, A.D. / Schneider, D.J. / Janjic, N.
External linksStructure / PubMed:26027732
MethodsX-ray diffraction
Resolution2.447 Å
Structure data

PDB-4zbn:
Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor
Method: X-RAY DIFFRACTION / Resolution: 2.447 Å

Chemicals

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsImmune system/DNA / Complex / Aptamer / Immune system-DNA complex

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