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Structure paper

TitleStructural Dynamics of the Cereblon Ligand Binding Domain.
Journal, issue, pagesPlos One, Vol. 10, Page 28342-, Year 2015
Publish dateMar 10, 2015 (structure data deposition date)
AuthorsHartmann, M.D. / Boichenko, I. / Coles, M. / Lupas, A.N. / Hernandez Alvarez, B.
External linksPlos One / PubMed:26024445
MethodsX-ray diffraction
Resolution1.2 - 2.9 Å
Structure data

PDB-5amh:
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, trigonal crystal form
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-5ami:
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Wash I structure
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-5amj:
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Wash II structure
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-5amk:
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in multiple conformations, hexagonal crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-EF2:
S-Thalidomide / medication*YM

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

Source
  • magnetospirillum gryphiswaldense (magnetotactic)
KeywordsSIGNALING PROTEIN / TERATOGENICITY / AROMATIC CAGE

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