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Structure paper

TitleDNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition.
Journal, issue, pagesNucleic Acids Res., Vol. 43, Page 6075-6083, Year 2015
Publish dateDec 16, 2014 (structure data deposition date)
AuthorsChauleau, M. / Jacewicz, A. / Shuman, S.
External linksNucleic Acids Res. / PubMed:26007660
MethodsX-ray diffraction
Resolution1.5 - 2.25 Å
Structure data

PDB-4xba:
Hnt3
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-4ykl:
Hnt3 in complex with DNA and guanosine
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-GMP:
GUANOSINE

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-5GP:
GUANOSINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • schizosaccharomyces pombe (strain 972 / atcc 24843) (yeast)
  • synthetic construct (others)
KeywordsHYDROLASE / GMP / nucleotidyl transferase / Hydrolase/DNA / Hydrolase-DNA complex

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