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Structure paper

TitleStructures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.
Journal, issue, pagesNature, Vol. 523, Page 111-114, Year 2015
Publish dateFeb 2, 2015 (structure data deposition date)
AuthorsWebb, B.A. / Forouhar, F. / Szu, F.E. / Seetharaman, J. / Tong, L. / Barber, D.L.
External linksNature / PubMed:25985179
MethodsX-ray diffraction
Resolution3.1 - 3.4 Å
Structure data

PDB-4xyj:
Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-4xyk:
Crystal structure of human phosphofructokinase-1 in complex with ADP, Northeast Structural Genomics Consortium Target HR9275
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CO:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Structural Genomics / PSI-Biology / Protein Structure Initiative / Northeast Structural Genomics Consortium / NESG

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