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Structure paper

TitleStructural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Journal, issue, pagesSci Rep, Vol. 5, Page 10103-10103, Year 2015
Publish dateJul 22, 2014 (structure data deposition date)
AuthorsMorales, R.A. / MacRaild, C.A. / Seow, J. / Krishnarjuna, B. / Drinkwater, N. / Rouet, R. / Anders, R.F. / Christ, D. / McGowan, S. / Norton, R.S.
External linksSci Rep / PubMed:25965408
MethodsX-ray diffraction
Resolution1.208 - 1.7 Å
Structure data

PDB-4qxt:
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with FC27-MSP2 14-30
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

PDB-4qy8:
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30
Method: X-RAY DIFFRACTION / Resolution: 1.353 Å

PDB-4qyo:
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22
Method: X-RAY DIFFRACTION / Resolution: 1.208 Å

PDB-4r3s:
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • plasmodium falciparum k1 (eukaryote)
  • plasmodium falciparum 3d7 (eukaryote)
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsIMMUNE SYSTEM / Immunoglobulin fold / N-TERMINAL MSP2 / unstructured antigen

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