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Structure paper

TitleAn Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
Journal, issue, pagesPlos One, Vol. 10, Page e0126206-e0126206, Year 2015
Publish dateMar 2, 2015 (structure data deposition date)
AuthorsParker, M.L. / Boulanger, M.J.
External linksPlos One / PubMed:25955165
MethodsX-ray diffraction
Resolution1.93 - 2.2 Å
Structure data

PDB-4yiv:
Crystal structure of engineered TgAMA1 lacking the DII loop
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-4yiz:
Crystal structure of engineered TgAMA1 lacking the DII loop in complex with an Eimeria tenella RON2D3 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CD:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-CO:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-A2G:
2-acetamido-2-deoxy-alpha-D-galactopyranose

ChemComp-SO4:
SULFATE ION

Source
  • toxoplasma gondii me49 (eukaryote)
  • eimeria tenella (eukaryote)
KeywordsIMMUNE SYSTEM / Apicomplexa / invasion / moving junction / parasite / protein engineering / PAN domain

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