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TitlePotent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Journal, issue, pagesMol Oncol, Vol. 9, Page 1348-1358, Year 2015
Publish dateApr 21, 2015 (structure data deposition date)
AuthorsOden, F. / Marino, S.F. / Brand, J. / Scheu, S. / Kriegel, C. / Olal, D. / Takvorian, A. / Westermann, J. / Yilmaz, B. / Hinz, M. ...Oden, F. / Marino, S.F. / Brand, J. / Scheu, S. / Kriegel, C. / Olal, D. / Takvorian, A. / Westermann, J. / Yilmaz, B. / Hinz, M. / Daumke, O. / Hopken, U.E. / Muller, G. / Lipp, M.
External linksMol Oncol / PubMed:25953704
MethodsX-ray diffraction
Resolution1.895 Å
Structure data

PDB-4zfo:
J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269)
Method: X-RAY DIFFRACTION / Resolution: 1.895 Å

Chemicals

ChemComp-CU:
COPPER (II) ION

ChemComp-BTB:
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / antibody Fab-ligand complex anti-BCMA anti-tumor

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