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Structure paper

TitleStructures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.
Journal, issue, pagesActa Crystallogr F Struct Biol Commun, Vol. 71, Page 566-571, Year 2015
Publish dateMar 31, 2010 (structure data deposition date)
AuthorsAbendroth, J. / Choi, R. / Wall, A. / Clifton, M.C. / Lukacs, C.M. / Staker, B.L. / Van Voorhis, W. / Myler, P. / Lorimer, D.D. / Edwards, T.E.
External linksActa Crystallogr F Struct Biol Commun / PubMed:25945710
MethodsX-ray diffraction
Resolution1.7 - 2.3 Å
Structure data

PDB-3meb:
Structure of cytoplasmic aspartate aminotransferase from giardia lamblia
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4eu1:
Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4h51:
Crystal structure of a putative Aspartate Aminotransferase from Leishmania major Friedlin
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-4w5k:
Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei, K237A mutant
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-MLT:
D-MALATE

Source
  • giardia lamblia (eukaryote)
  • trypanosoma brucei (eukaryote)
  • leishmania major (eukaryote)
  • trypanosoma brucei brucei (eukaryote)
KeywordsTRANSFERASE / ASPARTATE AMINOTRANSFERASE / Aminotransferase / Pyridoxal phosphate / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease / SSGCID / pyridoxalphosphate lysine / mitochondrial / Leishmania major / Trypanosoma brucei

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