EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
ジャーナル・号・ページ	Cell(Cambridge,Mass. ), Vol. 161, Page 470-485, Year 2015
掲載日	2015年1月14日 (構造データの登録日)
著者	Wu, X. / Zhang, Z. / Schramm, C.A. / Joyce, M.G. / Do Kwon, Y. / Zhou, T. / Sheng, Z. / Zhang, B. / O'Dell, S. / McKee, K. ...Wu, X. / Zhang, Z. / Schramm, C.A. / Joyce, M.G. / Do Kwon, Y. / Zhou, T. / Sheng, Z. / Zhang, B. / O'Dell, S. / McKee, K. / Georgiev, I.S. / Chuang, G.Y. / Longo, N.S. / Lynch, R.M. / Saunders, K.O. / Soto, C. / Srivatsan, S. / Yang, Y. / Bailer, R.T. / Louder, M.K. / Mullikin, J.C. / Connors, M. / Kwong, P.D. / Mascola, J.R. / Shapiro, L.
リンク	Cell(Cambridge,Mass. ) / PubMed:25865483
手法	X線回折
解像度	1.69 - 3.39 Å
構造データ	PDB-4s1q: Crystal structure of a VRC01-lineage antibody, 45-VRC01.H03+06.D-001739, in complex with clade A/E HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4s1r: Crystal structure of a VRC01-lineage antibody, 45-VRC01.H08.F-117225, in complex with clade A/E HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 3.214 Å PDB-4s1s: Crystal structure of a VRC01-lineage antibody, 45-VRC01.H5.F-185917, in complex with clade A/E HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 3.39 Å PDB-4xmp: Crystal structure of broadly and potently neutralizing antibody VRC08 in complex with HIV-1 clade A strain Q842.d12 gp120 手法: X-RAY DIFFRACTION / 解像度: 1.7831 Å PDB-4xny: Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4xnz: Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120 手法: X-RAY DIFFRACTION / 解像度: 3.389 Å PDB-4xvs: Crystal structure of HIV-1 donor 45 d45-01dG5 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4xvt: Crystal structure of HIV-1 93TH057 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) 手法: X-RAY DIFFRACTION / 解像度: 1.69 Å
化合物	ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン ChemComp-HOH: WATER ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / HEPES / pH緩衝剤YM ChemComp-BU3*: (R,R)-2,3-BUTANEDIOL / (2R,3R)-2,3-ブタンジオ-ル
由来	human immunodeficiency virus 1 (ヒト免疫不全ウイルス) homo sapiens (ヒト)
キーワード	VIRAL PROTEIN/IMMUNE SYSTEM / HIV-1 / neutralizing antibodies / VRC01-lineage / antibody maturation / evolutionary rate / VIRAL PROTEIN-IMMUNE SYSTEM complex / VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR / VIRAL PROTEIN-IMMUNE SYSTEM-INHIBITOR complex / IMMUNE SYSTEM / Antibody / HIV-1 antibodyomics neutralizing antibody germline binding