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Structure paper

TitleMolecular Determinants for Recognition of Divergent Samhd1 Proteins by the Lentiviral Accessory Protein Vpx.
Journal, issue, pagesCell Host Microbe., Vol. 17, Page 489-, Year 2015
Publish dateFeb 20, 2015 (structure data deposition date)
AuthorsSchwefel, D. / Boucherit, V.C. / Christodoulou, E. / Walker, P.A. / Stoye, J.P. / Bishop, K.N. / Taylor, I.A.
External linksCell Host Microbe. / PubMed:25856754
MethodsX-ray diffraction
Resolution2.649 Å
Structure data

PDB-5aja:
Crystal structure of mandrill SAMHD1 (amino acid residues 1-114) bound to Vpx isolated from mandrill and human DCAF1 (amino acid residues 1058-1396)
Method: X-RAY DIFFRACTION / Resolution: 2.649 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • simian immunodeficiency virus
  • mandrillus sphinx (mandrill)
KeywordsVIRAL PROTEIN / SIV / ACCESSORY PROTEIN / RETROVIRAL RESTRICTION FACTOR / UBIQUITYLATION / PROTEASOMAL DEGRADATION

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