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Structure paper

TitleThe crystal structure of the PB2 cap-binding domain of influenza B virus reveals a novel cap recognition mechanism.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 9141-9149, Year 2015
Publish dateFeb 10, 2014 (structure data deposition date)
AuthorsLiu, Y. / Yang, Y. / Fan, J. / He, R. / Luo, M. / Zheng, X.
External linksJ. Biol. Chem. / PubMed:25691568
MethodsX-ray diffraction
Resolution1.8 - 2.293 Å
Structure data

PDB-4or4:
Structure of Influenza B PB2 cap-binding domain with Q325F mutation complex with m7GDP
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

PDB-4or6:
Structure of Influenza B PB2 cap-binding domain with Q325F mutation complex with GDP
Method: X-RAY DIFFRACTION / Resolution: 2.293 Å

PDB-4q46:
The second structure of Influenza B PB2 cap-binding domain complex with GDP
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-M7G:
7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • influenza b virus
KeywordsVIRAL PROTEIN / cap binding

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