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Structure paper

TitleEvidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic-type serine/threonine kinase from Mycobacterium tuberculosis.
Journal, issue, pagesFebs J., Vol. 282, Page 1419-1431, Year 2015
Publish dateJan 31, 2014 (structure data deposition date)
AuthorsRavala, S.K. / Singh, S. / Yadav, G.S. / Kumar, S. / Karthikeyan, S. / Chakraborti, P.K.
External linksFebs J. / PubMed:25665034
MethodsX-ray diffraction
Resolution2.03 Å
Structure data

PDB-4ow8:
Crystal structure of kinase domain of PknA from Mtb
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTRANSFERASE / PknA / kinase / drug target / Mtb

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