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TitleDifferential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.
Journal, issue, pagesBiochemistry, Vol. 54, Page 1294-1305, Year 2015
Publish dateDec 5, 2012 (structure data deposition date)
AuthorsSzulik, M.W. / Pallan, P.S. / Nocek, B. / Voehler, M. / Banerjee, S. / Brooks, S. / Joachimiak, A. / Egli, M. / Eichman, B.F. / Stone, M.P.
External linksBiochemistry / PubMed:25632825
MethodsX-ray diffraction
Resolution1.02 - 1.95 Å
Structure data

PDB-4i9v:
The atomic structure of 5-Hydroxymethyl 2'-deoxycitidine base paired with 2'-deoxyguanosine in Dickerson Drew Dodecamer
Method: X-RAY DIFFRACTION / Resolution: 1.02 Å

PDB-4pwm:
Crystal structure of Dickerson Drew Dodecamer with 5-carboxycytosine
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-4qc7:
Dodecamer structure of 5-formylcytosine containing DNA
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-SPK:
SPERMINE (FULLY PROTONATED FORM)

ChemComp-HOH:
WATER

Source
  • synthetic dna (others)
KeywordsDNA / 5-Hydroxymethyl 2' deoxycitidine / 5-hydroxymethyl-dC adduct / modified DDD / Dodecamer of B-DNA / DNA crystal structure / Dickerson Drew Dodecamer / 5-carboxycytidine / 5-carboxycytosine / double helix / B-form DNA / 5-formylcytosine

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