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TitleMechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 6715-6730, Year 2015
Publish dateSep 30, 2014 (structure data deposition date)
AuthorsDutta, K. / Varshney, A.K. / Franklin, M.C. / Goger, M. / Wang, X. / Fries, B.C.
External linksJ. Biol. Chem. / PubMed:25572397
MethodsX-ray diffraction
Resolution1.8 - 2.698 Å
Structure data

PDB-4rgm:
Structure of Staphylococcal Enterotoxin B bound to the neutralizing antibody 20B1
Method: X-RAY DIFFRACTION / Resolution: 2.689 Å

PDB-4rgn:
Structure of Staphylococcal Enterotoxin B bound to two neutralizing antibodies, 14G8 and 6D3
Method: X-RAY DIFFRACTION / Resolution: 2.698 Å

PDB-4rgo:
Structure of Staphylococcal Enterotoxin B bound to the neutralizing antibody 14G8
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

Source
  • staphylococcus aureus (bacteria)
  • mus musculus (house mouse)
KeywordsTOXIN/IMMUNE SYSTEM / Neutralizing antibody / Staphylococcal enterotoxin B / TOXIN-IMMUNE SYSTEM complex

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