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-Structure paper
Title | Structure-based design and optimization of potent inhibitors of the adenoviral protease. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 25, Page 438-443, Year 2015 |
Publish date | Nov 13, 2014 (structure data deposition date) |
![]() | Grosche, P. / Sirockin, F. / Mac Sweeney, A. / Ramage, P. / Erbel, P. / Melkko, S. / Bernardi, A. / Hughes, N. / Ellis, D. / Combrink, K.D. ...Grosche, P. / Sirockin, F. / Mac Sweeney, A. / Ramage, P. / Erbel, P. / Melkko, S. / Bernardi, A. / Hughes, N. / Ellis, D. / Combrink, K.D. / Jarousse, N. / Altmann, E. |
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Methods | X-ray diffraction |
Resolution | 1.03 - 2.4 Å |
Structure data | ![]() PDB-4wx4: ![]() PDB-4wx6: ![]() PDB-4wx7: |
Chemicals | ![]() ChemComp-3VF: ![]() ChemComp-EPE: ![]() ChemComp-GLY: ![]() ChemComp-HOH: ![]() ChemComp-3VK: ![]() ChemComp-3VJ: |
Source |
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![]() | HYDROLASE / cysteine protease / inhibitor / cofactor / deubiquitinase / covalent |