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Structure paper

TitleHuman Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10.
Journal, issue, pagesFebs J., Vol. 282, Page 746-768, Year 2015
Publish dateJul 15, 2014 (structure data deposition date)
AuthorsOnwukwe, G.U. / Kursula, P. / Koski, M.K. / Schmitz, W. / Wierenga, R.K.
External linksFebs J. / PubMed:25515061
MethodsX-ray diffraction
Resolution1.88 - 2.85 Å
Structure data

PDB-4u18:
Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase (ISO-ECI2)
Method: X-RAY DIFFRACTION / Resolution: 2.64 Å

PDB-4u19:
Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase V349A mutant (ISOA-ECI2)
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-4u1a:
Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase helix-10 deletion mutant (ISOB-ECI2)
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsISOMERASE / PECI / enoy-CoA isomerase / crotonase / beta-oxidation

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